Jenna Mendelson, PhD

Jenna Mendelson
Jenna will begin a postdoc position in September, 2026 with John Elrod at Temple University
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Education

Ph.D., Physiology, University of Minnesota, Department of Integrative Biology and Physiology, 2026 
Thesis: Large animal investigations of the right heart: Big insights into right ventricular failure.
Advisors: Kurt Prins, MD, PhD

B.S.,Ohio State University, Pharmaceutical Sciences, 2016

Awards, Grants & Recognition

  • UMN Beatrice Z. Milne and Theodore Brandenburg Award, 2026
  • UMN J. Jacob Kaplan Award, 2026
  • UMN Steer Pruitt Award, 2026
  • Visscher Symposium Young Investigator Competition Award winner (1st place), 2025
  • UMN Dr. Marvin and Hadassah Bacaner Research Award, 2025
  • American Heart Association 3CPR Council Cournand and Comroe Early Career Investigator Award Winner (1st place), 2024
  • F31 Grant, National Heart, Lung, and Blood Institute; National Institutes of Health. “Mechanisms of Large Animal RV Dysfunction”, 2024-present.
  • University of Minnesota Dean’s Distinguished Graduate Fellowship, 2021

Publications

  1. Mendelson JB, Sternbach JD, Kim M, Raveendran RM, Moon RA, Hartweck LM, Tollison W, Carney JP, Markowski T, Higgins L, Prins SE, Kazmirczak F, Prins KW. Multimodality Molecular Profiling Nominates Targetable Mechanisms in Progressive RV Dysfunction. Circ Res (resubmitted after revisions), 2026.
  2. Prins SE, Sternbach JD, Mendelson JB, Markowski T, Higgins, L, Carney JP, Tollison W, Choudhary G, Prins KW. Proteomics Defines Shared and Divergent Alterations in the Right Atrium and Right Ventricle in Porcine Right Heart Failure. bioRxiv, 2026.
  3. Mendelson JB, Sternbach JD, Kim M, Moon RA, Hartweck LM, Clark SR, Tollison W, Lahti MT, Carney JP, Markowski T, Higgins L, Kazmirczak F, Prins KW. GP130 antagonism enhances porcine RV function. Circ Res, 2025.
  4. Mendelson JB, Sternbach JD, Kim M, Moon RA, Blake JC, Raveendran RM, Hartweck LM, Tollison W, Lahti MT, Carney JP, Kazmirczak F, Choudhary G, Prins KW. Single-nucleus RNAseq Defines the Cellular and Molecular Landscape of the Dysfunctional Right Atrium in Pulmonary Artery Banded Swine. Circ Res, 2025.
  5. Abreu P, Moon RA, Mendelson JB, Markowski T, Higgins L, Murray K, Guerrero C, Blake JC, Prisco SZ, Prins KW. Proteomic and Metabolomic Profiling Nominates Druggable Targets and Biomarkers for Pulmonary Arterial Hypertension Associated Myopathy and Exercise Intolerance. JHLT, 2025.
  6. Prisco SZ, Blake M, Kazmirczak F, Moon RA, Kremer BP, Hartweck LM, Kim M, Vogel NT, Mendelson JB, Moutsoglou D, Thennappan T, Prins KW. Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. Circ Heart Fail, 2025
  7. Moon RA, Vogel NT, Mendelson JB, Hartweck LM, Carney JP, Kim M, Gardner MK, Prisco SZ, Prins KW. 17β-Estradiol Counteracts Pathological Microtubule Remodeling to Enhance Cardiac Function. bioRxiv, 2025
  8. Kazmirczak F, Moon RT, Vogel NT, Tollison W, Lahti MT, Carney JP, Mendelson JB, Markwoski T, Higgens L, Murray K, Guerrero C, Prins KW. Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs. Am J Respir Crit Care Med, 2024.
  9. Kazmirczak F*, Vogel NT*, Prisco SZ*, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Mancipe NC, Markowski T, Higgens L, Guerrero C, Kremer B, Blake ML, Rhodes CJ, Williams JW, Brittain EL, Prins KW. Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension. Circ Res, 2024. (*contributed equally).
  10. Prisco SZ, Hartweck LM, Kazmirczak F, Mendelson JB, Deng SL, Blake M, Lahiri SK, Wehrens XH, Prins KW. Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation, 2024.
  11. Mendelson JB, Sternbach JD, Doyle MJ, Mills L, Hartweck LM, Tollison W, Carney JP, Lahti MT, Bianco RW, Kalra R, Kazmirczak F, Hindmarch C, Archer SL, Prins KW, Martin CM. A Multi-Omic and Multi-Species Analysis of Right Ventricular Dysfunction. JHLT, 2023.
  12. Zhang N, Harsch B, Zhang MJ, Gyberg DJ, Stevens JA, Wagner BM, Mendelson JB, Patterson MT, Orchard DA, Healy CL, Williams JW, Townsend D, Shearer GC, Murphy KA, O’Connell TD. FFAR4 Regulates Cardiac Oxylipin Balance to Promote Inflammation Resolution in HFpEF Secondary to Metabolic Syndrome. J Lipid Res, 2023.
  13. Kazmircsak F, Hartweck LM, Vogel NT, Mendelson JB, Park AK, Raveendram RM, O-Uchi J, Jhun BS, Prisco SZ, Prins KW. Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules. JACC Basic Transl Sci, 2023.
  14. Aiello SR, Mendelson JB, Baetiong A, Radhakrishnan JR, Gazmrui, RJ. Targeted Delivery of Electrical Shocks and Epinephrine, Guided by Ventricular Fibrillation Amplitude Spectral Area, Reduces Electrical and Adrenergic Myocardial Burden, Improving Survival in Swine. JAHA, 2021.