Education
Ph.D., Physiology, University of Minnesota, Department of Integrative Biology and Physiology, 2026
Thesis:Redox perturbations in muscular dystrophy: mechanistic insights into eccentric contraction–induced force loss.
Advisors:James Ervast, Ph.D., Dawn Lowe, PhD
M.D., University of Minnesota, Medical School, (Exp. 2028)
B.S., Marquette University, Physiological Sciences, 2016
Awards, Grants & Recognition
- World Muscle Society Travel Award, 2025
- Allan Hemingway Scholarship, University of Minnesota
- Principal Investigator—Katherine Fallon, National Heart, Lung, and Blood Institute; National Institutes of Health Contribution of hydrogen sulfide to Duchenne muscular
dystrophy pathophysiology 1F30HL176040-01 , 08/01/2024-Present - Trainee—Dawn Lowe, PhD; Edgar Arriaga, PhD; Laura Niedernhofer, MD, PhD, National Institute on Aging; National Institutes of Health, Functional Multi-omics of Aging 2T32AG029796-16, 05/01/2023-04/30/2024
- Trainee—Yoji Shimizu, PhD, Medical Scientist Training Program, 5T32GM008244-34, 07/2020-present
Publications
- Southern WM, Johnson EE, Fasbender EK, Fallon KS, Cavazos CL, Lowe DA, Rodney GG, Ervasti JM. Impaired hydrogen sulfide biosynthesis underlies eccentric contraction-induced force loss in dystrophin-deficient skeletal muscle. J Clin Invest 2025 Jan 14;135(5):e176942. PMID: 39808494
- Demonbreun AR, Bogdanovic E, Vaught LA, Reiser, NL, Fallon KS, Long AM, Oosterbaan CC, Hadhazy M, Page PG, Joseph PRB, Cowen G, Telenson AM, Khatri A, Sadlier KR, Vassar R, McNally EM. A conserved annexin A6-mediated membrane repair mechanism in muscle, heart, and nerve. JCI Insight. 2022 Jul 22;7(14). PMID: 35866481
- Demonbreun AR, Fallon KS, Oosterbaan C, Vaught LA, Reiser NL, Bogdanovic E, Velez MP, Salamone IM, Page PGT, Hadhazy M, Quattrocelli M, Barefield DY, Wood L, Gonzalez P, Morris C, McNally EM. Anti-latent TGF-beta binding protein 4 (LTBP4) antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Science Translational Medicine. 2021 Sep 8;13(610). PMID: 34516828
- McDade TW, McNally M, Zelikovich A, D’Aquila RD, Mustanski B, Miller A, Vaught L, Reiser N, Bogdanovich E, Fallon KS, Demonbreun A. High seroprevalence for SARS-CoV-2 among household members of essential workers detected using a dried blood spot assay. PLoS One. 2020 Aug 14;15 (8). PMCID: PMC7428174
- Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page PG, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. Dis Model Mech.2019 Nov 4;13(2). PMCID: PMC6906631
- Demonbreun AR, Fallon KS, Oosterbaan CC, Bogdanovich E, Warner JL, Sell J, Page PGT, Quattrocelli M, Barefield DY, McNally EM. Recombinant annexin A6 promotes membrane repair and protects against muscle injury. J Clin. Invest. 2019 Nov 1;129(11):4657-4670. PMCID: PMC6488756